翻訳と辞書 Words near each other ・ Indonesia at the Olympics ・ Indonesia at the Paralympics ・ Indonesia Calling ・ Indonesia Christian Church ・ Indonesia Commodity and Derivatives Exchange ・ Indole-2-monooxygenase ・ Indole-3-acetaldehyde oxidase ・ Indole-3-acetaldehyde reductase (NADH) ・ Indole-3-acetaldehyde reductase (NADPH) ・ Indole-3-acetate beta-glucosyltransferase ・ Indole-3-acetic acid ・ Indole-3-butyric acid ・ Indole-3-carbinol ・ Indole-3-carboxylate decarboxylase ・ Indole-3-glycerol-phosphate lyase ・ Indole-3-glycerol-phosphate synthase ・ Indole-3-pyruvate monooxygenase ・ Indole-5,6-quinone ・ Indoleacetaldoxime dehydratase ・ Indoleacetate—lysine synthetase ・ Indoleacetylglucose—inositol O-acyltransferase ・ Indoleamine 2,3-dioxygenase ・ Indolelactate dehydrogenase ・ Indolence ・ Indolent ・ Indolent Records ・ Indoleptipsius ・ Indolepyruvate C-methyltransferase ・ Indolepyruvate decarboxylase ・ Indolepyruvate ferredoxin oxidoreductase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Indole-3-glycerol-phosphate synthase ： ウィキペディア英語版 Indole-3-glycerol-phosphate synthase In enzymology, an indole-3-glycerol-phosphate synthase (IGPS) () is an enzyme that catalyzes the chemical reaction :1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate $\backslash rightleftharpoons$ 1-C-(indol-3-yl)-glycerol 3-phosphate + CO2 + H2O Hence, this enzyme has one substrate, 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate, but 3 products: 1-C-(indol-3-yl)-glycerol 3-phosphate, CO2, and H2O. This enzyme belongs to the family of lyases, to be specific, the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (1-C-(indol-3-yl)glycerol-3-phosphate-forming ). Other names in common use include indoleglycerol phosphate synthetase, indoleglycerol phosphate synthase, indole-3-glycerophosphate synthase, 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate, and carboxy-lyase (cyclizing). This enzyme participates in phenylalanine, tyrosine and tryptophan biosynthesis and two-component system - general. It employs one cofactor, pyruvate. ==Structural studies== In some bacteria, IGPS is a single chain enzyme. In others, such as ''Escherichia coli'', it is the N-terminal domain of a bifunctional enzyme that also catalyses N-(5'-phosphoribosyl)anthranilate isomerase () (PRAI) activity, the third step of tryptophan biosynthesis. In fungi, IGPS is the central domain of a trifunctional enzyme that contains a PRAI C-terminal domain and a glutamine amidotransferase () (GATase) N-terminal domain. A structure of the IGPS domain of the bifunctional enzyme from the mesophilic bacterium ''E. coli'' (eIGPS) has been compared with the monomeric indole-3-glycerol phosphate synthase from the hyperthermophilic archaeon ''Sulfolobus solfataricus'' (sIGPS). Both are single-domain (beta/alpha)8 barrel proteins, with one (eIGPS) or two (sIGPS) additional helices inserted before the first beta strand. As of late 2007, 11 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , and . 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Indole-3-glycerol-phosphate synthase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.